A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer
Status:
Completed
Trial end date:
2018-01-08
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as carboplatin and pegylated liposomal
doxorubicin hydrochloride (PLD) work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Everolimus may stop the growth
of tumor cells by blocking some of the enzymes needed for cell growth. Giving carboplatin and
PLD together with everolimus may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of everolimus when
given together with carboplatin and PLD in treating patients with relapsed ovarian
epithelial, fallopian tube, or peritoneal cavity cancer