A Study of Chlorhexidine in the Prevention of HIV-1 Transmission From Mothers to Their Babies
Status:
Completed
Trial end date:
2007-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find the best strength of chlorhexidine (a solution that
kills germs), for washing the mother's vagina during labor and the newborn baby, that may
reduce the chance of HIV being passed from an HIV-positive mother to the baby.
When used as a wash on the vagina during labor, and on a newborn shortly after birth, a
higher dose of chlorhexidine is more likely to reduce the rate of HIV-1 transmission from
mother to baby. Laboratory tests suggest that a higher dose of chlorhexidine will be more
effective in killing HIV.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)