Overview

A Study of Comparison of TACE Combination With and Without EBRT for Advanced HCC

Status:
Recruiting
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
This clinical trial is a prospective, randomized, controlled and multicenter study.And the trial is going to enroll better control intrahepatic tumors for hepatocellular carcinoma(HCC) patients who meet the inclusion criterion.The patients were divided into two groups, the group A by TACE and the other group B by external- beam radiotherapy(EBRT) after 2 times TACE. Then the therapeutic effects and toxicities of TACE and EBRT are evaluated during the follow-up period. The study design plans to enroll 300 patients, and each group includes 150 cases.
Phase:
Phase 3
Details
Lead Sponsor:
Shanghai Zhongshan Hospital
Collaborators:
309th Hospital of Chinese People's Liberation Army
affiliated Zhongshan hospital of Dalian university
Anhui Provincial Hospital
Beijing Cancer Hospital
Changhai Hospital
First Affiliated Hospital of Fujian Medical University
First Affiliated Hospital of Guangxi Medical University
First Affiliated Hospital of Xinjiang Medical University
First Affiliated Hospital of Zhejiang University
Fudan University
Fujian Cancer Hospital
Heilongjiang Provincial Agricultural Reclamation General Hospital
Jilin University
Longyan First Hospital, Affiliated to Fujian Medical University
Peking University First Hospital
Qingdao University
Shanghai 10th People's Hospital
Subei People's Hospital of Jiangsu Province,Yangzhou University
The 4th people's hospital of Wuxi City,Affiliated to Jiangnan Universit
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
The First Affiliated Hospital of Xiamen University
The Third Affiliated Hospital of Qiqihar Medical Vniversitiy
West China Hospital
Xinqiao Hospital of Chongqing
Zhongshan Hospital Xiamen University
Treatments:
Chlorotrianisene
Doxorubicin
Ethiodized Oil
Liposomal doxorubicin