A Study of Effect of Food and a Proton Pump Inhibitor on Selpercatinib (LY3527723) in Healthy Participants
Status:
Completed
Trial end date:
2018-09-13
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to assess the effect of food on how fast selpercatinib gets
into the bloodstream and how long it takes the body to remove it after a high-fat meal, and
the effect of a change in gastric pH after multiple doses of omeprazole on how fast
selpercatinib gets into the bloodstream and how long it takes the body to remove it when
administered under fasted and fed conditions in healthy participants. The study will also
evaluate the safety and tolerability of selpercatinib in healthy participants. The study will
last up to 33 days excluding the screening period.