Overview

A Study of ISIS 416858 Administered Subcutaneously to Participants With End-Stage Renal Disease (ESRD) on Hemodialysis

Status:
Completed
Trial end date:
2019-07-10
Target enrollment:
Participant gender:
Summary
Evaluation of safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of ISIS 416858 for up to 204 participants with ESRD receiving chronic hemodialysis as assessed by FXI activity reduction.
Phase:
Phase 2
Details
Lead Sponsor:
Ionis Pharmaceuticals, Inc.
Collaborator:
Bayer
Treatments:
Riboflavin