A Study of LY2484595 on Pharmacokinetics in Healthy Participants
Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
This is a 2-part study. Part 1 is to determine the safety and tolerability in healthy
participants of increasing daily doses of LY2484595 for 14 days to achieve a blood level of
LY2484595 much higher than what is needed for therapy. The amount of study drug that reaches
the bloodstream and the time it takes for the body to get rid of it will be determined. The
effect of the study drug on factors in the blood related to cholesterol will be measured.
Part 2 is to determine how ketoconazole affects how much of the study drug, LY2484595, gets
into the bloodstream and how long it takes to get rid of it. Information about any side
effects that may occur will also be collected.