Overview

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Status:
Recruiting
Trial end date:
2025-07-01
Target enrollment:
0
Participant gender:
All
Summary
The main purpose of this study is to determine the efficacy and safety of LY3972406 in adult participants with moderate-to-severe plaque psoriasis.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Eli Lilly and Company
Criteria
Inclusion Criteria:

- Have moderate-to-severe chronic plaque psoriasis for at least 6 months prior to
baseline

- Have venous access sufficient to allow for blood sampling

- Are able to swallow oral medication

- Agree to skin biopsies

Exclusion Criteria:

- Have any other skin conditions, excluding plaque psoriasis

- Have a current or recent acute, active infection

- Have manifestations of other autoimmune diseases, such as systemic lupus
erythematosus.

- Are lactating or breastfeeding women