Overview

A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children

Status:
Active, not recruiting
Trial end date:
2021-10-30
Target enrollment:
Participant gender:
Summary
The main aims of this study are to learn how lanadelumab moves through a child's body and if the children have any medical problems from lanadelumab. Other aims are to learn if prophylactic treatment with lanadelumab reduces the number and severity of HAE attacks in children, how lanadelumab affects the child's body, and if the children develop antibodies to lanadelumab. The study doctors will treat acute HAE attacks according to their standard practice. Participants will receive lanadelumab for up to 52 weeks. When they start treatment, participants will visit their clinic every week for the first 4 weeks. Then, they will visit their clinic every 4 weeks during treatment.
Phase:
Phase 3
Details
Lead Sponsor:
Shire
Treatments:
Antibodies, Monoclonal