A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity
Status:
Recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
Taxane-induced peripheral neuropathy (TIPN) caused by paclitaxel is a dose-limiting toxicity.
The main symptoms of discomfort are numbness, tingling, and burning sensations in the
glove-sock-like distribution of the limbs. At present, there are few effective methods for
clinical treatment of TIPN, and there is no widely agreed consensus on effective treatment in
the world. Therefore, it is of great clinical significance and practical value to carry out
clinical research to explore drugs to relieve TIPN.