A Study of Neoadjuvant Photodynamic Immunomodulation for Colon Cancer
Status:
Withdrawn
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
The central hypothesis for this study is that it is safe and feasible to administer
intraluminal photodynamic therapy (PDT) to colon cancers by colonoscopy to induce localized
inflammatory/immune response. The objective is to demonstrate the feasibility and safety of
PDT to colon cancer patients administered before surgery and to characterize the
inflammatory/immune response at the tumor site and systemically. The long-term objective of
these studies is to modify he natural biology of colorectal cancers and improve patient
survival.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Edward Nelson
Collaborators:
National Cancer Institute (NCI) University of California, Irvine