A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712)
Status:
Completed
Trial end date:
2011-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the onset of action of two commercially available
over-the-counter antihistamines (Loratadine and
Fexofenadine) in a model of seasonal allergic rhinitis (SAR). Participants undergo
sensitization exposures to Mountain Cedar (juniperus ashei) pollen in a Biogenics Research
Chamber; those who demonstrate an adequate allergic response determined by the Major Symptom
Complex (MSC) score will then receive drug.