Overview

A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal A

Status:
Terminated

Trial end date:
2019-11-04

Target enrollment:

Participant gender:

Summary

The purpose of this study is to compare the efficacy and safety of PEGylated Recombinant Human Hyaluronidase (PEGPH20) combined with nab-paclitaxel plus gemcitabine (PAG treatment), compared with placebo combined with nab-paclitaxel plus gemcitabine (AG treatment), in participants with hyaluronan (HA)-high Stage IV previously untreated pancreatic ductal adenocarcinoma (PDA).

Phase:

Phase 3

Details

Lead Sponsor:

Halozyme Therapeutics

Treatments:

Albumin-Bound Paclitaxel
Gemcitabine
Hyaluronic Acid
Paclitaxel