A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this trial is to study the efficacy of preoperative radiation therapy and capecitabine in locally advanced rectal cancer.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alberta Health Services
• Treatments: Capecitabine

Criteria

Inclusion Criteria:

• Biopsy - proven rectal cancer

• Transmural rectal wall invasion

• Karnofsky performance status >70

• Normal bone marrow, liver and kidney function

Exclusion Criteria:

• Distant metastases

• Prior pelvic radiation

• Inflammatory bowel disease

• Severe ischemic heart disease

• Anticoagulant therapy

• Pregnancy