A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults
Status:
Recruiting
Trial end date:
2021-11-30
Target enrollment:
Participant gender:
Summary
The main aim of this study is to check how itraconazole and mefenamic acid affect the way
soticlestat is processed by the body.
The study will have 2 parts. Participants can only participate in one study part.
Part 1: Participants will check into the study clinic to receive soticlestat, four days later
they will begin receiving itraconazole and will stay in the clinic for 11 more days,
receiving soticlestat in combination with itraconazole on one of those days. Participants
will be contacted about 8 days after leaving the clinic for follow-up.
Part 2: Participants will check into the study clinic to receive soticlestat, four days later
they will begin receiving mefenamic acid and will stay in the clinic for 7 more days,
receiving soticlestat in combination with mefenamic acid on one of those days.. Participants
will be contacted about 9 days after leaving the clinic for follow-up.