A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to see if it is safe and effective to give one of three different triple-drug combinations to HIV-infected patients who have never been treated with anti-HIV drugs.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Treatments: Didanosine; Indinavir; Lamivudine; Nevirapine; Stavudine

Criteria

Inclusion Criteria

Patients must have:

• Diagnosed asymptomatic HIV infection.

• HIV-1 RNA greater than 500 copies/ml.

• CD4+ T-cell count greater than 200/mm3.

• Never received antiretroviral therapy.

Exclusion Criteria

Co-existing Condition:

Excluded:

Severe non-HIV-related disease.

Patients with the following prior conditions are excluded:

History of neuropathy.

Prior Medication:

Excluded:

• Investigational drug within 1 month prior to study.

• Immunomodulatory drug within 1 month prior to study.

Prior Treatment:

Excluded:

• Radiation therapy within past month.

• Chemotherapy within past month.