A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
Status:
Recruiting
Trial end date:
2027-06-28
Target enrollment:
Participant gender:
Summary
The main aim of this study is to learn about the effect of treatment with vedolizumab IV
(vedolizumab) together with adalimumab or vedolizumab together with ustekinumab in adults
with moderate to severe Crohn's Disease, and the effect of treatment with vedolizumab alone,
after the dual targeted treatment.
The study is conducted in two parts. In Part A, participants will receive the dual targeted
treatment (vedolizumab together with either adalimumab or ustekinumab). In part B,
participants will receive vedolizumab only. Part B will include participants who responded to
the treatment in Part A.
Each participant will be followed up for at least 26 weeks after the last dose of treatment.