A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Status:
Not yet recruiting
Trial end date:
2027-07-09
Target enrollment:
Participant gender:
Summary
The main aim of this study is to learn about the effect of treatment with vedolizumab IV
(vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis
(UC). Another aim is to learn about treatment with Vedolizumab alone after the double
treatment.
All participants will receive vedolizumab together with tofacitinib for 8 weeks and will be
checked for response. Participants who show a response to the treatment after 8 weeks will be
treated with vedolizumab alone for an additional 44 weeks.
Each participant will be followed up for at least 26 weeks after the last dose of
vedolizumab.