Overview

A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective

Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
This protocol is a phase I/II, study of ascorbic acid (AA) infusions combined with treatment with sorafenib versus treatment with sorafenib alone in subjects with metastatic hepatocellular carcinoma. The phase I aspect will assess the safety and efficacy of the concurrent treatments and the phase II aspect will utilize CT (computer-tomography) scans to assess overall tumor response rate and evaluate disease progression
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Thomas Jefferson University
Treatments:
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Ascorbic Acid
Molecular Mechanisms of Pharmacological Action
Niacinamide
Sorafenib
Vitamins