A Study of the Effect of Different Doses of Difluprednate Eye Drops on the Intraocular Pressure After Phacoemulsification

• Status: Recruiting
• Trial end date: 2023-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims at detecting the minimum effective daily dose and duration of difluprednate that can be used to treat postoperative inflammation after phacoemulsification without increasing the intraocular pressure, and whether it can be safely given within the first 24 hours after the operation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kafrelsheikh University
• Treatments: Difluprednate; Ophthalmic Solutions

Criteria

Inclusion Criteria:

• Age 40-80

• Grade 1 to 4 nuclear cataract LOCS II

• Cumulative dissipated energy CDE 1 to 10

• Done by a single surgeon using the chopping technique

Exclusion Criteria:

• History of uveitis

• the use of topical or systemic steroids on the last post-operative day

• Intraoperative or postoperative complications

• Intraoperative iris manipulations or phaco traume