A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
Status:
Completed
Trial end date:
2012-03-03
Target enrollment:
Participant gender:
Summary
This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic
blood pressure in participants with mild to moderate hypertension in addition to safety and
tolerability. The study hypothesis is that MK-8457 does not increase systolic blood pressure
to a clinically significant extent, as measured by 24-hour mean ambulatory systolic blood
pressure change from baseline after 10 days of dosing.