A Study of the Effects of Oral Prednisone in Patients With Rheumatoid Arthritis (MK0000-088)

• Status: Completed
• Trial end date: 2009-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will compare the effects of prednisone vs placebo on synovial blood flow and overall DAS (disease activity score) in patients with rheumatoid arthritis.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Prednisone

Criteria

Inclusion Criteria:

• Patient is willing to limit alcohol intake to 3 or less beverages per day

• Patient agrees to use only acetaminophen/paracetamol for breakthrough pain

Exclusion Criteria:

• Patient has other inflammatory arthritis (e.g. lupus). Patient has had major surgery or donated or lost 1 unit of blood in the last 4 weeks

• Patient has a history of drug or alcohol abuse in the last 2 years

• Patient has had a vaccine (with a live or attenuated virus) in the last two weeks