A Study of the Efficacy of Fecal Microbiota Transplantation(FMT) in the Treatment of Schizophrenia
Status:
Not yet recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study was to explore whether repeated oral fecal capsules could improve
outcomes in patients with schizophrenia receiving conventional antipsychotic drugs. This
study was divided into screening period (1 week) and treatment period (8 weeks). Subjects who
met the inclusion criteria during the screening period entered the treatment period. During
the treatment period, the patients were divided into two groups: oral fecal bacteria capsules
+ antipsychotics group; Oral placebo + antipsychotic group. During the follow-up period, both
groups were treated with stable dose of antipsychotic drugs during the treatment period.
Before and after the intervention, venous blood samples of patients were collected for
routine tests such as liver and kidney function to determine the safety of treatment. The
scale evaluated the improvement of patients' psychotic symptoms to determine the efficacy and
safety of FMT combined with antipsychotics.
Phase:
N/A
Details
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University