A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral Doses
Status:
Recruiting
Trial end date:
2022-08-01
Target enrollment:
Participant gender:
Summary
This is a Phase I Healthy volunteer study with the primary objective to evaluate the safety
and pharmacokinetics profile of AX-158. The first part will evaluate single ascending dose
administrations. A substudy will be performed as well to evaluate possible impact of food on
drug exposure if administered under fasted or fed state. The second part will evaluate
multiple ascending dose over 10 days of dosing in fed or fast state depending on the results
of the substudy food effect on AX-158.