A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)

• Status: Not yet recruiting
• Trial end date: 2020-10-16
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess levels in blood plasma of BMS-986278 and the food effect in healthy participants.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bristol-Myers Squibb
• Treatments: Esomeprazole

Criteria

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

• Healthy participants, as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs, and clinical laboratory determinations in the opinion of the investigator

• Women and men must agree to follow specific methods of contraception

Exclusion Criteria:

• Women of childbearing potential (WOCBP) and Women who are pregnant or breastfeeding

• Any significant acute or chronic medical condition that presents a potential risk to the participant and/or that may compromise the objectives of the study

• Exposure to any investigational drug or placebo within 4 weeks of first study treatment administration.

• History of any significant drug and/or food allergies (such as anaphylaxis or hepatotoxicity)

Other protocol-defined inclusion/exclusion criteria apply