A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies

• Status: Completed
• Trial end date: 2012-11-01

Summary

The purpose of this study is to evaluate the potential effects of ketoconazole on blood levels of trabectedin after administration to patients with advanced malignancies.

• Phase: Phase 1/Phase 2

Details

• Lead Sponsor: Janssen Research & Development, LLC
• Collaborator: PharmaMar
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ketoconazole; Trabectedin