A Study to Compare the Efficacy of Rapydan Versus Tetracaine Gel

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Male

Summary

Tetracaine gel 4% is a topical anaesthetic gel commonly used in the UK that contains 40 mg of tetracaine base per gram. Adequate anaesthesia can usually be achieved following a 30 minute application time for venopuncture and a 45 minute application time for venous cannulation. The hypothesis is that Rapydan medicated plaster is more effective than tetracaine gel in preventing venous cannulation related pain when applied for the recommended treatment durations of 30 minutes and 45 minutes respectively.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jazz Pharmaceuticals
• Treatments: Tetracaine

Criteria

Inclusion Criteria:

• Healthy male subjects of any race, 18 yrs or older

• No clinically significant findings on physical exam

• Signed informed consent

Exclusion Criteria:

• Damaged, denuded or broken skin at the designated site for application of the medicated plaster or gel.

• Know allergies to lidocaine, tetracaine or other local anaesthetics

• Concomitant use of prescription strength analgesics