A Study to Compare the Safety and Imaging Pattern of Cyclotron-produced Technetium (CTC) vs. Generator-produced Technetium (G-PERT) in People With Thyroid Disorders Who Need Surgery

• Status: Unknown status
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: All

Summary

A 99mTc Pertechnetate (G-PERT) scan is a nuclear medicine test that can create an image of the thyroid gland and other organs. G-PERT is approved by Health Canada for the direct imaging and measurement of thyroid uptake.

Doctors and researchers at the University of Alberta have developed a new method of producing 99mTc Pertechnetate (called CTC). It is made in a cyclotron at the Medical Isotope and Cyclotron Facility (MICF) at the University of Alberta, Edmonton, Alberta. This new production method will provide another source of 99mTc Pertechnetate. The aim of this study is to confirm that CTC is safe and can be used interchangeably with G-PERT.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alexander McEwan; Todd McMullen
• Treatments: Sodium Pertechnetate Tc 99m

Criteria

Inclusion Criteria:

1. Male or female ≥ 18 years of age and < 80 years of age.

2. Have a proven or suspected thyroid pathology that requires surgery by standard clinical criteria.

3. Able and willing to follow instructions and comply with the protocol.

4. Provide written informed consent prior to participation in the study.

Exclusion Criteria:

1. Nursing or pregnant females.