Overview

A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users

Status:
Terminated

Trial end date:
2017-11-28

Target enrollment:

Participant gender:

Summary

This will be a single-dose, randomized, double-blind, active- and placebo-controlled, double dummy, 6-way crossover study to determine the abuse potential of tozadenant relative to d-amphetamine and placebo, when administered orally in healthy non-dependent, recreational polydrug users with stimulant experience, under fed conditions. Each subject will participate in a medical Screening visit, a 4-day (3-night) qualification (drug discrimination) visit, six 3-day (2-night) treatment periods, and a follow-up visit.

Phase:

Phase 1

Details

Lead Sponsor:

Biotie Therapies Inc.

Collaborator:

Acorda Therapeutics

Treatments:

Amphetamine
Dextroamphetamine