Overview

A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)

Status:
Terminated
Trial end date:
2011-07-12
Target enrollment:
Participant gender:
Summary
This is a Phase III, randomized, double blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of ocrelizumab compared to placebo when combined with a single stable background immunosuppressive medication and a corticosteroid regimen in patients with moderately to severely active systemic lupus erythematosus, who do not have moderate to severe glomerulonephritis.
Phase:
Phase 3
Details
Lead Sponsor:
Genentech, Inc.
Collaborator:
Roche Pharma AG
Treatments:
Azathioprine
Immunosuppressive Agents
Methotrexate
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone Hemisuccinate
Mycophenolic Acid
Ocrelizumab
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Prednisone