A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS)

• Status: Completed
• Trial end date: 2018-06-30
• Target enrollment: 0
• Participant gender: All

Summary

A study to assess the effect of heat application on the delivery profile of Corplex™ Donepezil Transdermal Delivery System (TDS)

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Corium International Inc.; Corium, Inc.
• Treatments: Donepezil

Criteria

Inclusion Criteria:

• Healthy, adult, male or female ≥ 30 years of age

Exclusion Criteria:

• History of any illness that, in the opinion of the investigator, might confound the results of the study or poses an additional risk to the subject by participation in the study

• History or presence of alcoholism or drug abuse within the past 2 years prior to the first study product treatment

• History or presence of hypersensitivity or idiosyncratic reaction to the study products or related compounds

• History of significant multiple and/or severe allergies, or has had an anaphylactic reaction or significant intolerability to prescription or nonprescription drugs

• History or presence of excessive sweating

• History or presence of hairy skin on application sites

• History or presence of significant skin damage or disease at application sites

• Any medical or surgical procedure or trauma within 28 days prior to the first study product treatment