Overview

A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Status:
Completed
Trial end date:
2017-09-06
Target enrollment:
Participant gender:
Summary
This study will be a single center, open-label, 2-period, fixed-sequence, Phase 1 drug-drug interaction study in healthy subjects. The primary purpose of this study is to evaluate the effect of itraconazole on the PK of ipatasertib and its primary metabolite (G-037720).
Phase:
Phase 1
Details
Lead Sponsor:
Hoffmann-La Roche
Treatments:
Hydroxyitraconazole
Itraconazole