A Study to Evaluate the Mass Balance Absorption and AME of VBR

• Status: Completed
• Trial end date: 2020-12-22
• Target enrollment: 0
• Participant gender: Male

Summary

This Phase 1 Study will determine the mass balance recovery, absorption, metabolism, and excretion of [14C] Vebicorvir in healthy male subjects

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assembly Biosciences

Criteria

• Consent

• Male between 18 and 55 years of age (inclusive) at the time of Screening

• Body mass index (BMI) between ≥18.0 kg/m2 and ≤32.0 kg/m2 at Screening; body weight between ≥55.0 kg and ≤100.0 kg at Screening

• Considered to be in good health by the Investigator

Exclusion Criteria:

• History or presence of any condition (e.g., chronic diarrhea) or prior surgery (e.g., gastric bypass)

• Clinically significant abnormal medical history

• History of cancer that has not been in full remission for >5 years

• Acute illness within 14 days prior to study drug administration