Overview

A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus

Status:
Completed
Trial end date:
2008-08-25
Target enrollment:
Participant gender:
Summary
This is a Phase II/III, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of rituximab compared with placebo when combined with a single stable background immunosuppressive medication in subjects with moderate to severe systemic lupus erythematosus (SLE). The primary efficacy endpoint of the trial will be evaluated at 52 weeks.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Genentech, Inc.
Treatments:
Acetaminophen
Diphenhydramine
Prednisone
Promethazine
Rituximab