A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to see if nitazoxanide (NTZ) can be used to treat AIDS patients suffering from cryptosporidiosis (diarrhea caused by the parasite Cryptosporidium).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Romark Laboratories L.C.
• Treatments: Nitazoxanide

Criteria

Inclusion Criteria

Patients may be eligible for this study if they:

• Are 3 to 65 years old (need consent of parent or guardian if under 18).

• Have AIDS.

• Have a CD4 count less than or equal to 200 cells/mm3. (Note: Patients with a CD4 count greater than 200 cells/mm3 but who have had cryptosporidiosis for at least 4 weeks may be eligible for this study.)

• Test positive for the parasite Cryptosporidium and have severe diarrhea (at least 4 bowel movements per day) for at least 2 weeks.

• Have received treatment for cryptosporidiosis but have become reinfected after treatment.

• Agree to practice abstinence or use effective methods of birth control (such as a condom) before and during the study.

Exclusion Criteria

Patients will not be eligible for this study if they:

• Are pregnant.

• Are infected with certain other parasites.

• Have a history of certain intestinal diseases.

• Have received certain medications.