Overview

A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects

Status:
Completed
Trial end date:
2017-08-22
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of Entinostat on the bioavailability of Midazolam. The primary objective is to evaluate the effect of a single oral dose of entinostat on the pharmacokinetics (PK) of a single oral dose of midazolam in healthy subjects. The secondary objective is to evaluate the safety and tolerability of combined administration of entinostat and midazolam in healthy subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Syndax Pharmaceuticals
Treatments:
Entinostat
Histone Deacetylase Inhibitors
Midazolam