Overview

A Trial Comparing GSK1349572 50mg Plus Abacavir/Lamivudine Once Daily to Atripla (Also Called The SINGLE Trial)

Status:
Completed
Trial end date:
2015-12-03
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to assess the non-inferior antiviral activity of GSK1349572 50 mg plus Abacavir/Lamivudine once daily versus Efavirenz/Emtricitabine/Tenofovir disoproxil fumarate (ATRIPLA® a trade mark of Bristol-Myers Squibb and Gilead Sciences LLC) over 48 weeks; non-inferiority will also be tested at Week 96. This study will be conducted in HIV-1 infected ART-naïve adult subjects. Long term antiviral activity, tolerability, safety, and development of viral resistance will be evaluated.
Phase:
Phase 3
Details
Lead Sponsor:
ViiV Healthcare
Collaborators:
GlaxoSmithKline
Shionogi
Treatments:
Abacavir
Dideoxynucleosides
Dolutegravir
Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Lamivudine