A Trial Evaluating Tolerability of Grazax Treatment in Combination With Antihistamine
Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
Many grass pollen allergic subjects treated with immunotherapy tablets experience treatment
related adverse events when initiating treatment.
The majority are local allergic reactions within the mouth and/or throat, and most of these
reactions are mild or moderate. It is anticipated that intake of antihistamine before
initiation of Grazax treatment would most likely reduce the discomfort associated with
initiation of Grazax treatment. So this trial was to investigate if administration of
antihistamine prior to initiation of Grazax treatment results in a reduction of subjects
reporting local allergic reactions.