Overview

A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer - QUILT-3.007

Status:
Completed
Trial end date:
2018-12-19
Target enrollment:
Participant gender:
Summary
This open-label, non-randomized, dose escalation phase I biomarker trial of the triplet regimen of AMG 479, everolimus, and panitumumab for subjects with refractory advanced solid tumors is designed to assess the safety and tolerability of this combination as well as preliminary efficacy.
Phase:
Phase 1
Details
Lead Sponsor:
Herbert Hurwitz, MD
Jeffrey Clarke
Collaborators:
Amgen
NantCell, Inc.
Novartis Pharmaceuticals
Treatments:
Antibodies, Monoclonal
Everolimus
Panitumumab
Sirolimus