A Trial of Clobetasol Propionate Versus Hydrocortisone in Children With Alopecia Areata
Status:
Completed
Trial end date:
2003-08-01
Target enrollment:
Participant gender:
Summary
The use of topical steroids in the treatment of alopecia areata in children is common
practice. However, no particular potency of steroid is accepted as the standard treatment due
to the paucity of high quality evidence in the dermatology literature to substantiate their
use. Two randomized controlled trials exist assessing topical steroid efficacy in this
disorder, both have methodological limitations. The question remains as to which topical
steroid is safe and efficacious for use. We performed a double blinded controlled trial to
assess the usefulness of a class 1 topical steroid (clobestasol proprionate 0.05%) compared
with a class 7 topical steroid (hydrocortisone 1%) in children with alopecia areata.