Overview

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Status:
Completed

Trial end date:
2018-07-06

Target enrollment:

Participant gender:

Summary

The primary objective of the study is to evaluate the effect of itraconazole (a potent cytochrome P450 isoenzyme [CYP]3A inhibitor) on the pharmacokinetics of IW-1973.

Phase:

Phase 1

Details

Lead Sponsor:

Cyclerion Therapeutics
Ironwood Pharmaceuticals, Inc.

Treatments:

Hydroxyitraconazole
Itraconazole
Praliciguat