A Trial to Study the Effect of Vitamin D Supplementation on Glucose and Insulin Metabolism in Centrally Obese Men

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of the study is to evaluate the change in glucose and insulin metabolism(early markers for development of diabetes) after 6 weeks of weekly Vitamin D supplementation. As vitamin D has been reported to be associated with lipid levels, CRP and blood pressure , we will also be measuring the changes in these variables.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sitaram Bhartia Institute of Science and Research
• Treatments: Ergocalciferols; Insulin; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Male

• ≥35 years of age

• Waist circumference ≥78 cm

Exclusion Criteria:

• Diabetic- Fasting Blood Sugar >126 mg/dl or on anti-diabetic medication

• BP>140/90 or on anti-hypertensive medication

• Receiving Vitamin D or calcium supplementation

• Chronic disease-renal/hepatic/malignancy/gastrointestinal

• On any medication within the last one month which could potentially influence insulin secretion, insulin sensitivity, Vitamin D or Calcium metabolism

• Febrile illness or infective morbidity in the past 10 days

• Past history of nephrolithiasis