A Two Arm Trial of Axitinib and Carboplatin/Paclitaxel in Melanoma
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
This is a two arm prospective Phase II pilot trial designed to determine the optimal duration
of break between axitinib and chemotherapy with carboplatin/paclitaxel in melanoma. In this
study, 6 patients will be enrolled to Arm A, the FLT PET scan (3'deoxy-3'-18F-Fluorothymidine
positron emission tomography scans)cohort. 30 patients will be enrolled to Arm B, the
treatment-only cohort. 36 total patients will be enrolled. The treatment schedule will be the
same in either cohort, with the exception of the FLT PET scans.