ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients

• Status: Terminated
• Trial end date: 2016-06-24
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effects of Angiotension Converting Enzyme Inhibitors (ACE-I) during surgery and in the immediate postoperative period for patients undergoing elective total hip or knee arthroplasty.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Duke University
• Treatments: Angiotensin-Converting Enzyme Inhibitors

Criteria

Inclusion Criteria:

• Patients electing to undergo primary or revision total hip or knee arthroplasty

• Currently taking an ACE-I

Exclusion Criteria:

• Trauma patients

• Immunosuppressed patients (HIV/AIDS, organ transplant recipients, chemotherapy patients, chronic steroid use)

• Patients with history of severe hypertension related illness such as hypertension associated with stroke or myocardial infarction

• Patients in who continuation of their ACE-I is expressly mandated by their prescribing physician