Overview

AGILE (Early Phase Platform Trial for COVID-19)

Status:
Recruiting
Trial end date:
2022-04-30
Target enrollment:
Participant gender:
Summary
The AGILE platform master protocol allows incorporation of a range of identified and yet-to-be-identified candidates as potential treatments for adults with COVID-19 into the trial. Candidates will be added into the trial via candidate-specific trial (CST) protocols of this master protocol as appendices. Having one master protocol ensures different candidates are evaluated in the same consistent manor and opening up new trials for new candidates is more efficient. Inclusion of new candidates will be determined by the AGILE Scientific Advisory Board based on pre-clinical data, evidence in the clinical setting and GMP capabilities.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Liverpool
Collaborators:
Lancaster University
Liverpool School of Tropical Medicine
Liverpool University Hospitals NHS Foundation Trust
University of Cambridge
University of Southampton
Treatments:
Nitazoxanide