The purpose of this study is to determine the safety and effectiveness of a multi-drug
chemotherapy regimen in adult patients with Acute Lymphoblastic Leukemia (ALL). We will use a
regimen that is often used in pediatric patients and we will add drugs called
PEG-asparaginase and E. coli asparaginase. PEG-asparaginase has been given as an injection in
the past and has been used in treatment with both children and adults with ALL. Information
from those other research studies suggests that intravenous PEG-asparaginase has been
administered safely in both children and adults. We hope to gain more information about the
participants disease and how it responds to standard chemotherapy drugs used to treat ALL>
Phase:
Phase 2
Details
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborators:
Boston Children's Hospital Boston Children’s Hospital Massachusetts General Hospital NCIC Clinical Trials Group