AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA

• Status: Unknown status
• Trial end date: 2018-07-30
• Target enrollment: 0
• Participant gender: All

Summary

The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on cardiopulmonary resuscitation results and outcomes in out-of-hospital cardiac arrest patients.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Asan Medical Center
• Treatments: Arginine Vasopressin; Vasopressins

Criteria

Inclusion Criteria:

• non-traumatic adult out-of-hospital cardiac arrest (OHCA) patients with non-shockable arrest rhythm

Exclusion Criteria:

• OHCA with terminal illness documented by medical record, under hospice care, with pregnancy, with pre-documented 'Do Not Resuscitate' card

• trauma patients

• age < 18 years old

• failed arterial line insertion within 6 minutes after randomization

• Extracorporeal cardiopulmonary resuscitation

• Time interval between arrest and ED arrival > 60 minutes

• ROSC within 6 minutes after ED arrival

• Diastolic Blood Pressure > 20 mmHg during resuscitation