ASPIRE Pilot: Comparing Self-collected HPV Testing With Visual Inspection With Acetic Acid Screening for Cervical Cancer

• Status: Completed
• Trial end date: 2015-12-29
• Target enrollment: 0
• Participant gender: Female

Summary

Cervical cancer remains a public health burden, particularly in developing countries such as sub-saharan Africa where the infrastructure for organized screening programs does not exist. As a result, other screening modalities (visual inspection with acetic acid) are the standard of care in such regions. It is now known, persistent infection with an oncogenic Human papillomavirus (HPV) type is a necessary precursor of cervical cancer and evidence is showing HPV testing is a potential, safe and effective alternative to cytology testing (The Pap smear). This study is evaluating the feasibility and acceptance of HPV self-collection vs. VIA in a cohort of women from Kisenyi, Uganda.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of British Columbia
• Collaborator: Makerere University
• Treatments: Acetic Acid; Retinol acetate

Criteria

Inclusion Criteria:

• Aged 30-65yrs

• Living or working in community of Kisenyi, Uganda

• Access to mobile telephone

• Fluent in Luganda, Somali or English

• Competent to provide informed consent

Exclusion Criteria:

• Known to be pregnant at study entry (self-reported)

• Complete hysterectomy

• Prior diagnosis or treatment of cervical dysplasia or cervical cancer