ASTHMA (AntibioticS To Help Manage Asthma) Pilot Study
Status:
Completed
Trial end date:
2002-09-01
Target enrollment:
Participant gender:
Summary
The ASTHMA Pilot Study is a randomized, controlled, parallel group clinical trial of 6 weekly
doses of azithromycin (cumulative dose 4800 mg) or placebo as adjunctive treatment in
addition to usual care for adults with stable persistent asthma, with final follow up at 3
months after completion of study medication.
The hypothesis to be tested is that antibiotic treatment will improve asthma at followup, and
that this improvement will be limited to patients with evidence of C. pneumoniae infection.
The secondary hypothesis is that randomized, controlled treatment trials can be carried out
successfully in a geographically dispersed practice-based research network.