AZD0530 and Gemcitabine in Locally Advanced/Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery
Status:
Completed
Trial end date:
2012-01-06
Target enrollment:
Participant gender:
Summary
RATIONALE: AZD0530 may stop the growth of tumor cells by blocking some of the enzymes needed
for cell growth. Drugs used in chemotherapy, such as gemcitabine, work in different ways to
stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving AZD0530 together with gemcitabine may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of AZD0530 when
given together with gemcitabine and to see how well they work in treating patients with
locally advanced or metastatic pancreatic cancer that cannot be removed by surgery.