Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients
Status:
Completed
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to obtain and assay human aqueous samples following
pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite®
(pH 7.2) from patients undergoing routine cataract surgery in order to evaluate the aqueous
concentration of the two formulations.Study hypothesis: The aqueous humor concentration 45
minutes following dosing of 0.1% Brimonidine Purite™ (pH 7.8) is comparable with 0.15%
Brimonidine Purite® (pH 7.2)